Trypanosoma brucei

  • Disease: Human African trypanosomiasis (HAT), Sleeping sickness
  • Habitat in human: Blood (but not inside red blood cells)
  • Diagnosis of infection: Microscopic examination of blood to detect trypomastigotes
Morphological Features of Trypomastigote
  • Size: 14 – 33 mm in length
  • Long and spindle shaped; some short and stumpy
  • Nucleus is centrally located
  • Undulating membrane along the body
  • A single flagellum – runs along undulating membrane and extend freely from anterior end
  • Kinetoplast is small and located at the posterior end
Magnification x100